-IBIS-1.5.0-
tx
reproductive system
cervical dysplasia
diagnoses
definition and etiology
definition:
Dysplasia of the uterine cervix. Epithelial atypia involving part of the squamous epithelium; more common in young women.
etiology:
Cervical dysplasia is now considered a sexually-transmitted disease because of the implicated role of human papilloma virus (HPV) in bringing about tissue changes.
It is considered a precancerous lesion, since dysplastic changes often precede malignant transformation.
Risk factors include:
early age of first intercourse
multiple partners
sexual exposure to men who have HPV
sexual exposure to men sexually exposed to women with CIN
sexual exposure to men of low socioeconomic status
Co-factors in development of cervical cancer include:
smoking
poor diet
long-term oral contraceptive use
chronic cervicitis
HSV infection
immune compromise
environmental carcinogens
signs and symptoms
This is a microscopic finding usually found routinely with a PAP smear.
course and prognosis
The condition may either progress through various stages, potentially ending in cervical intraepithelial neoplasia (CIN), or regress spontaneously or with treatment. Prognosis is excellent with appropriate treatment. Conventional treatment includes laser surgery, but does not address the underlying causes. Regular PAP smears are essential to monitor cervical status.
differential diagnosis
carcinoma.
footnotes