-IBIS-1.5.0-
tx
reproductive system
cervical dysplasia
diagnoses

definition and etiology

definition:
Dysplasia of the uterine cervix. Epithelial atypia involving part of the squamous epithelium; more common in young women.

etiology:
Cervical dysplasia is now considered a sexually-transmitted disease because of the implicated role of human papilloma virus (HPV) in bringing about tissue changes.
It is considered a precancerous lesion, since dysplastic changes often precede malignant transformation.

Risk factors include:
• early age of first intercourse
• multiple partners
• sexual exposure to men who have HPV
• sexual exposure to men sexually exposed to women with CIN
• sexual exposure to men of low socioeconomic status

Co-factors in development of cervical cancer include:
• smoking
• poor diet
• long-term oral contraceptive use
• chronic cervicitis
• HSV infection
• immune compromise
• environmental carcinogens

signs and symptoms

This is a microscopic finding usually found routinely with a PAP smear.

course and prognosis

The condition may either progress through various stages, potentially ending in cervical intraepithelial neoplasia (CIN), or regress spontaneously or with treatment. Prognosis is excellent with appropriate treatment. Conventional treatment includes laser surgery, but does not address the underlying causes. Regular PAP smears are essential to monitor cervical status.

differential diagnosis

• carcinoma.


footnotes