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toxidrome
Quinine-like toxidrome
botanicals
definition
quinine-like toxidrome
the following toxicity information is largely derived from poisonings, overdoses and research on isolated constituents; used with appropriate clinical judgment and cautious prescribing, herbs are safe and efficacious
plants included:
» Hydrastis canadensis
reported to cause a quinine-like toxidrome characterized by a sensation of rushing in the ears, a sense of noisiness, and gastrointestinal disturbances, especially gastric warmth (Phillips, p. 17)
generalized gastrointestinal effects: internal and external ulcerant with nausea, vomiting, diarrhea; with time leading to mydriasis, vertigo, insomnia, and hallucinations; occasionally accompanied by a feeling of oppression in the chest, bradycardia, cyanosis, and respiratory disturbances (Duke, pp. 238-239; von Oettingen, p. 379)
footnotes
Duke, J.A. 1985. C.R.C. Handbook of Medicinal Herbs. Boca Raton, FL: The C.R.C. Press.
Phillips, C.D. 1879. Materia Medica and Therapeutics: Vegetable Kingdom. New York: William Wood and Company.
von Oettingen, W.F. 1958. Poisoning: A Guide to Clinical Diagnosis and Treatment. Philadelphia: W.B. Saunders and Company.